Cheaper Alternatives to Trelegy Ellipta: Most Effective, Best Price
speciality medications
Trelegy Ellipta for COPD or severe asthma can make an incredible difference in the safety and daily comfort of people who have these conditions.
If you or a loved one suffers from asthma or COPD, you probably know this. Trelegy Ellipta is everywhere these days, and there’s a good reason for that. It works, and it works well.
But, of course, there’s also Trelegy Ellipta’s price tag – which can be considerable.
We won’t keep you waiting.
In the United States, one month of Trelegy Ellipta can run you around $700.00-$800.00 per month – or well over $7,000.00 per year.
That, in a nutshell, is why so many patients search online for phrases like “Is there a cheaper alternative to Trelegy?” or “What is a good substitute for Trelegy?”
If you’re one of them, you’re in good company. And you’re also in the right place.
For one thing, here, through NorthWestPharmacy.com, you can buy that same month of brand Trelegy Ellipta for around $120.00 for 60 doses.
But that’s not all. We also provide reliable, accessible information about Trelegy Ellipta’s cheaper alternatives to help you make the most informed possible decision about your health.
Here, we’ll explore the most effective alternatives to Trelegy Ellipta, from newer triple-therapy inhalers like Breztri Aerosphere to more affordable double therapies such as Symbicort and Advair.
We’ll also look at international and Canadian pricing, since buying Trelegy or its substitutes online from Canada or internationally can make a dramatic difference in affordability.
What Is Trelegy Ellipta, and Why Is It So Expensive?
Trelegy Ellipta is a once-daily inhaler that combines three types of medication into one device:
- Fluticasone furoate (inhaled corticosteroid, reduces inflammation in the lungs)
- Umeclidinium (long-acting muscarinic antagonist, relaxes airway muscles)
- Vilanterol (long-acting beta agonist, keeps airways open)
Together, these three drug classes are known as ICS, LAMA, and LABA:
- ICS (Inhaled Corticosteroid): Helps calm airway inflammation, making it easier to breathe and reducing flare-ups.
- LAMA (Long-Acting Muscarinic Antagonist): Relaxes the airway muscles over a long period of time, preventing them from tightening.
- LABA (Long-Acting Beta Agonist): Works alongside the LAMA to keep the airways open and improve airflow.
These three types of medication together, an ICS + LAMA + LABA combination, is recommended for patients who continue to experience COPD symptoms despite using double-therapy inhalers.
In other words, if one medication alone doesn’t help you, and two medications together also don’t seem to help you achieve your health goals, maybe it’s time for three.
This is why Trelegy Ellipta is so popular.
This triple threat of a medication can, when used as intended and prescribed, reduce exacerbations, improve lung function, and support long-term disease management.
This is also one of the reasons why Trelegy Ellipta is so expensive.
Manufacturing a medication with three times the active ingredients costs a pretty penny. And the mere fact that the drug is so effective helps increase market demand – which influences Trelegy Ellipta’s manufacturer to take advantage of that demand while it can.
There are a few other reasons why Trelegy Ellipta is so expensive:
- Patent exclusivity: Trelegy Ellipta is still under patent protection, which means no generic alternative is available yet in the United States.
- Pricing system: Unlike Canada, the U.S. doesn’t regulate drug prices, leaving manufacturers free to set high retail costs.
- Insurance limitations: Many insurers require “step therapy” – or trying cheaper options first – before approving Trelegy Ellipta. Even when approved, copays can remain high.
For these and potentially many other reasons, often, patients taking Trelegy Ellipta turn to the internet for answers.
Is there another way?
Is There a Cheaper Alternative to Trelegy Ellipta?
The short answer: Yes.
… But the “best” option depends on your medical needs.
Consider this:
- If you need the full triple therapy offered by Trelegy Ellipta, there are other triple inhalers to think about, like the Breztri Aerosphere, that may be covered differently by insurance.
- If your doctor determines you may not need the steroid component, double-therapy inhalers (so, for example, LAMA + LABA) can be significantly cheaper, especially where generics exist.
- For patients open to international options, ordering Trelegy Ellipta or any of its alternatives from an online and international Canadian pharmacy website can result in steep savings.
Triple Therapy Alternatives to Trelegy Ellipta
When patients ask their doctor for an alternative to Trelegy Ellipta, the most direct substitutes are other triple therapy inhalers.
These inhalers help control inflammation, keep the airways open, and reduce flare-ups.
The benefit of triple therapy is convenience: instead of juggling multiple inhalers, patients only need to use one.
Breztri Aerosphere as a Trelegy Ellipta Alternative
Among the triple therapy options, Breztri Aerosphere is the closest match to Trelegy available in the United States.
Breztri combines budesonide (ICS), glycopyrrolate (LAMA), and formoterol (LABA). Like Trelegy, it’s taken once or twice daily and aims to reduce COPD exacerbations while improving lung function over the long term.
The device itself is slightly different, though.
Breztri is delivered through an Aerosphere inhaler, which feels different from Trelegy’s Ellipta device. Some patients find the switch easy, while others notice it takes a bit of adjustment. Effectiveness, however, is comparable, with clinical studies showing similar outcomes in reducing COPD flare-ups.
You can buy brand Breztri Aerosphere through NorthWestPharmacy.com for $170.00 per inhaler. There’s a generic for even less.
Trimbow as a Trelegy Ellipta Alternative
Trimbow is a triple therapy inhaler that contains beclometasone, formoterol, and glycopyrronium.
Trimbow isn’t widely available in the U.S., but it is approved and prescribed in many European countries and can sometimes be accessed through international or Canadian pharmacy websites.
The benefit of Trimbow is similar to Trelegy: one device, three medicines. For patients who have access to it, Trimbow can be a solid substitute.
Enerzair Breezhaler as a Trelegy Ellipta Alternative
Enerzair Breezhaler, another triple therapy, contains mometasone, indacaterol, and glycopyrronium.
Enerzair is approved in select markets, particularly in Europe, but is not yet common in the U.S.
Unlike Trelegy, Enerzair uses the Breezhaler system, which requires loading capsules into the inhaler for each use.
This makes it slightly less convenient than pre-loaded devices, but many patients still find it manageable once they get used to the routine.
Double Therapy Alternatives to Trelegy Ellipta
Not every patient with COPD or asthma requires a triple-therapy inhaler. For some, a double-therapy inhaler can provide enough control over symptoms while costing far less.
These inhalers usually combine either:
- ICS + LABA (inhaled corticosteroid + long-acting beta agonist), or
- LAMA + LABA (long-acting muscarinic antagonist + long-acting beta agonist).
Doctors often recommend double therapies when symptoms are moderate or when a patient can’t tolerate the steroid component of triple therapy.
Anoro Ellipta
Anoro Ellipta is made by the same manufacturer as Trelegy. (You might have guessed that, given the two medications share half their names.)
Anoro Ellipta and Trelegy Ellipta also share two of Trelegy’s three components – umeclidinium (LAMA) and vilanterol (LABA).
The main difference is that it does not include fluticasone, the steroid. For patients who don’t need an anti-inflammatory, Anoro can be a simpler and often more affordable option.
You can buy brand Anoro Ellipta through NorthWestPharmacy.com for about $140.00 per unit.
Stiolto Respimat
Stiolto Respimat combines tiotropium (LAMA) and olodaterol (LABA).
It’s another non-steroid option that helps relax airway muscles and improve long-term breathing function.
The Respimat device does require a slightly different inhalation technique than Ellipta devices, but many patients adapt quickly.
You can buy brand Stiolto Respimat through NorthWestPharmacy.com for about $175.00 per device.
Bevespi Aerosphere
Bevespi Aerosphere pairs glycopyrrolate (LAMA) with formoterol (LABA).
Because it lacks the steroid, it may not control inflammation as effectively as Trelegy, but for milder disease, it can be a good option to consider.
You can buy brand Bevespi Aerosphere through NorthWestPharmacy.com for about $280.00 per device or the generic for less than that.
Symbicort
Symbicort is a combination of budesonide (ICS) and formoterol (LABA).
One major advantage of Symbicort is that it’s got a generic now widely available in many markets, which can make it significantly more affordable than Trelegy.
You can buy brand Symbicort through NorthWestPharmacy.com for about $85.00 per device with the generic from us being much cheaper still.
Advair
Advair, another ICS + LABA inhaler, combines fluticasone with salmeterol.
Like Symbicort, it has been on the market for years, and generic Advair is available.
Because it uses the same steroid (fluticasone) as Trelegy, patients switching from Trelegy to Advair may notice less of a transition in how it feels to use. Advair’s lower price point makes it one of the most popular cheaper alternatives to Trelegy Ellipta.
You can buy brand Advair through NorthWestPharmacy.com for about $150.00 per inhaler with the generic costing much less.
Breo Ellipta
Breo Ellipta delivers fluticasone and vilanterol (ICS + LABA).
It’s another option for patients who need two of Trelegy’s three ingredients but not the third. Pricing is often lower than Trelegy, though it remains a brand-only medication.
You can buy brand Breo Ellipta through NorthWestPharmacy.com for about $136.00 per device.
Dulera
Dulera pairs mometasone (ICS) with formoterol (LABA).
Like Symbicort, it’s primarily used in asthma treatment, but it can sometimes be prescribed for COPD.
While not as common as other inhalers on this list, it offers another ICS + LABA option if cost or coverage align in its favor.
You can buy brand Dulera through NorthWestPharmacy.com for about $220.00 per device.
Is There a Generic Trelegy Ellipta?
Generic Trelegy Ellipta is not available in the United States, no.
In the States, there isn’t a generic through at least 2030, so it will be a while before you see low-cost generic alternatives to Trelegy Ellipta in your corner pharmacy.
That said, you may be able to find extremely close generic substitutes or generic alternatives to Trelegy Ellipta through an international pharmacy, as long as you trust that pharmacy to provide authentic, safe medications. Generic Trelegy Ellipta is now available through NorthWestPharmacy.com.
(A quick way to tell if you’re working with a trustworthy pharmacy website is to check and see if the site you’re looking at is on CIPA’s safe list.)
As just one example, here, through NorthWestPharmacy.com, you can buy a one-month supply of generic fluticasone furoate/umeclidinium/vilanterol trifenatate for about $120.00.
How to Get Trelegy Ellipta Cheaper Without Sacrificing Safety
If you and your doctor determine Trelegy Ellipta is the best medication for your condition or for other reasons you’d rather avoid Trelegy Ellipta alternatives, there are still ways to reduce costs.
Just a few of the avenues you might consider taking include:
Checking manufacturer patient assistance programs. Sometimes, manufacturers, including Trelegy Ellipta’s manufacturer offer co-pay cards or patient assistance for those who qualify.
Your doctor’s office is the best place to learn more about these opportunities and to learn more about eligibility requirements.
Review your insurance coverage. Contact your insurance representative and specifically ask if you can figure out a way to save on the medication of your choice.
In some cases, you may be able to figure out a beneficial path forward.
Of course, this does depend on your insurer, and, even if you do find an amenable solution, you’re still relying on your insurance company for help (and your ability to continue having insurance over the long term), which may make finding another solution, at least for backup, a good idea.
Order from a Canadian pharmacy. Licensed Canadian pharmacies and reputable international drugstores dispense the same brand-name Trelegy Ellipta, often at half the U.S. price.
Trelegy Ellipta Alternatives Can Help You Save (Big!)
Trelegy Ellipta is a powerful treatment for COPD and asthma, but it isn’t the only option.
As a triple therapy, it’s an efficient and effective way to treat even severe or stubborn cases – but it doesn’t work for everyone, and it’s certainly not the most affordable COPD or asthma med.
Alternatives like Breztri, Symbicort, Advair, and Anoro can offer effective relief, and in many cases, a far more manageable price point.
Some of them are made by the same manufacturer, or feature the exact same ingredients, just in different combinations.
It’s worth discussing with your doctor which will work for you, particularly if you’re interested in saving money!
However, know that if you’d like to try Trelegy Ellipta on a budget, that can still be very possible. You can buy brand-name or generic Trelegy Ellipta through NorthWestPharmacy.com for up to 82% savings when compared to American retail prices.
The key is working with your doctor to match the right inhaler to your medical needs and budget. With the growing number of effective alternatives — and safe, affordable online ordering options — you don’t have to choose between breathing easier and affording your medication.
When you’re ready to learn more about cheaper alternatives to Trelegy Ellipta, your team here at NorthWestPharmacy.com is ready to assist!
