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Save Money on the Best Prescription Retinoids

speciality medications

May 30, 2023
Best Prescription Retinoids

As far as skin-boosting benefits are concerned, prescription retinoids can be a game-changer for many people.

They’re effective exfoliants. They smooth out wrinkles and promote skin turnover. They even help with redness and acne.

The one problem? Prescription retinoids can be expensive.

Because ingredients like tretinoin are popular, sellers are popping up everywhere to take advantage of the buzz. Countless flashy websites promise miraculously glowy skin with their retinoid treatments – which often come with staggeringly high price tags and surprisingly low safety standards.

It’s key to remember that retinoids are prescription treatments. For the best results, you need access to the best treatments – from a certified, safe, and reputable online pharmacy.

Fortunately, taking this route doesn’t have to break the bank.

Here’s everything you need to know – including exactly how to get prescription retinoids online for a great price.

What are Prescription Retinoids?

Prescription retinoids are topical vitamin A-derived skin care treatments that exfoliate away dead skin and promote new skin cell production.

With this two-pronged approach, retinoids can unblock pores and make skin feel glowier and bouncier.

There are many types of retinoid skincare treatments. And several, such as Retin A, are available in various forms, including foams, creams, ointments, and gels.

Some effective treatments feature one potent prescription retinoid. In other cases, dermatologists recommend combination treatments utilizing retinoids alongside antibiotics or anti-inflammatories.

Regardless, as prescription retinoids can dry out skin, patients should always pair these treatments with a good moisturizer and sunscreen.

Are There Non-Cosmetic Uses for Prescription Retinoids?

Yes! Although retinoids are most commonly associated with skin care, that’s not the only way they can benefit patients.

Prescription retinoids are sometimes used in concert with other drugs as a cancer treatment. This type of tretinoin uses the same active ingredient as many skincare solutions, just in a different formulation and concentration.

Topical tretinoin should be reserved for external use only. Each retinoid product is made for a particular use and purpose.

What Are the Best Prescription Retinoids? (Your Go-To Guide)

The best prescription retinoid for you and your skin will probably differ significantly from what works for your friend or people you see online.

Remember, retinoid skin treatments are intense; they’re not the same as OTC acne soaps or moisturizing skincare creams. You need to partner with a qualified dermatologist to assess your skin’s needs and select the right retinoid for your goals.

Once you’ve determined which retinoid you need, you need to be able to buy it for an affordable price! That’s where can help.

Here are the top-selling prescription retinoids we offer through our site – along with helpful information, direct links, and how much you can save by shipping your prescription retinoids from Canada or internationally.

Retin A Cream

Retin A Cream (tretinoin) is an effective exfoliant with a heavy, satisfying texture.

Don’t let its feel fool you, though – as with any retinoid, you need to use a good moisturizer to counteract its drying effect.

How to Get Prescription Retin A Cream

Patients in the United States pay around $53.00 for a 20g tube of generic tretinoin cream, or approximately $2.60/g.

By purchasing prescription retinoid cream through an international online Canadian pharmacy instead, American patients can save up to 66%. Here, we sell 20g tubes of Retin A Cream for around $17.80, or about $0.90/g.

Retin A Micro Gel

Retin A Micro Gel (tretinoin) delivers tretinoin into a patient’s skin a little differently from Retin A Cream.

Think of it like a delayed-release oral medication: With a micro gel, the active ingredient is held in suspension and released over time, not all at once.

This can reduce possible side effects and may be a good choice for people who struggle with skin sensitivity.

How to Get Prescription Retin A Micro Gel

In America, generic tretinoin microgel costs around $260.00 for a 20g tube, or $13/g. Through, you can buy brand-name Retin A Micro Gel for about $2.25/g (up to 82% savings!), in a 20g tube that costs approximately $45.00.

Best Prescription Retinoids

Renova Cream .02%

Renova Cream .02% (tretinoin) is a heavier treatment that gives you an option to try a lower concentration of the active ingredient.

If you’ve tried a tretinoin cream at .05%, for example, and suffered skin sensitivity, Renova Cream .02% may be a viable alternative.

How to Get Prescription Renova Cream .02%

You can buy Renova Cream .02% through for about $360.00 for a 40g tube, or approximately $9.00 per gram.

Stieva A Cream - Alternative to Retin A Cream

Stieva A Cream (tretinoin cream) is a different brand of tretinoin cream, similar to Retin A Cream. It’s a good alternative with a slightly different formulation but the same prescription retinoid benefit.

How to Get Prescription Stieva A Cream

Unfortunately, Stieva A Cream is no longer available in the United States. If you prefer the feel and function of Stieva A Cream to its Retin A alternatives, you’ll need to think outside the box (or the country borders) to get it!

At, American patients can buy 50g of Stieva A Cream for approximately $36.00, or around $0.72/g.

Retin A Gel

Retin A Gel (tretinoin) is the gel formulation of Retin A Cream. It’s oil-free, has a lighter feel, and can be an excellent alternative to explore for those with oily or combination skin.

In addition, patients with rosacea often prefer the gel over the cream.

How to Get Prescription Retin A Gel

In America, the generic form of Retin A Gel retails for approximately $70.00 – $150.00 per 15g tube, depending on concentration. (That’s anywhere from $4.50 – $10.00 per gram.)

Here, you can buy brand-name Retin A Gel for about $26.00 for a 30g tube or around $0.85/g.


Vesanoid (tretinoin) leverages the same active ingredient as the other prescription treatments on this list, but it’s used very differently. Tretinoin can be taken orally alongside other drugs to treat certain types of cancer, including acute promyelocytic leukemia.

Specifically, tretinoin can encourage growth for normal cells and reduce the number of malignant, cancerous cells. Over time, this can help induce remission of cancer.

How to Get Prescription Vesanoid

Because Vesanoid is used in cancer treatment, it’s a costly drug.

After discussing your treatment strategies with your doctor and obtaining a valid prescription, you can buy Vesanoid from for around $11.00/capsule, usually sold in packs of 100 or more.


Melacare (hydroquinone/tretinoin/mometasone) is a topical treatment that can help reduce facial discoloration associated with melasma.

Tretinoin and its exfoliating, skin-growing power combine with an anti-inflammatory ingredient and a drug that influences how your skin produces pigment to promote a more even skin tone.

How to Get Prescription Melacare

Through, you can buy a 20g tube of a generic alternative for Melacare for about $38.00, or approximately $1.90/g.

Atralin Gel

Atralin Gel (tretinoin) is an anti-acne topical skincare treatment that focuses on exfoliating away dead skin cells, so your pores don’t get clogged and inflamed.

In addition, tretinoin can help vacuum away older skin and promote new skin growth by slowing down the rate at which your skin breaks down collagen and elastin.

As a result, after using Atralin Gel, patients enjoy clearer, smoother, and more even-feeling skin.

How to Get Prescription Atralin Gel

American patients can buy a 45g tube of Atralin Gel for around $560.00, or approximately $12.40/g, through

Renova Cream .05%

Renova Cream (tretinoin) is a retinoid skincare treatment that focuses first on anti-aging benefits and provides anti-acne care as a secondary perk. Its exfoliation can help reduce the appearance of fine lines and discoloration, clearing up acne and rosacea as needed.

How to Get Prescription Renova Cream .05%

Renova Cream .05% is not inexpensive. Americans pay $323.00 for a 40g tube of Renova Cream .05%, or about $8.00/g.

American patients seeking lower costs can buy generic Renova Cream .05% for approximately $1.30/g, or about $26.00 for a 20g tube.


ReFissa (tretinoin) can help promote collagen production and support the turnover rate of skin cells.

By doing this, ReFissa can help patients enjoy plump, glowy skin even as their skin naturally slows down collagen and hyaluronic acid production.

How to Get Prescription ReFissa

Through, you can buy a 40g tube of ReFissa for around $295.00, or approximately $7.40/g.

Tri-Luma Cream

Tri-Luma (fluocinolone acetonide/hydroquinone/tretinoin) provides the benefit of three active ingredients to boost skin health in one convenient application. It reduces inflammation and swelling and fights skin discoloration associated with melasma.

How to Get Prescription Tri-Luma Cream

At, a 30g tube of Tri-Luma Cream costs around $280.00, or around $9.40/g.

How to Get Prescription Retinoids in Three Simple Steps

Interested in the age-defying, acne-fighting benefits of prescription-strength retinoids?

Here’s exactly what you need to do to start trying retinoid treatment at home:

  1. Learn about your options. There are many different types of prescription retinoid skincare products. Before you purchase anything, take some time to price-check your options and educate yourself about what retinoids can do for you.
  2. Determine your skincare goals and discuss them with your doctor. For example, some prescription retinoids focus on reducing acne. Others promote skin cell turnover – and still others provide anti-aging benefits. Your doctor will assess your skin and recommend a product best suited for you.
  3. Purchase your prescription retinoids through a reputable, safe pharmacy. Your local pharmacy may stock tretinoin, but you'll probably want to check online to access a more comprehensive range of products. When you do, be aware of websites that offer to ship you potent skincare treatments without requiring a prescription or even having pharmacists on hand!

Common Side Effects of Prescription Retinoids

Although prescription retinoids can provide sought-after skincare results, they can produce unwanted side effects. These include:

  • Warm-feeling skin
  • Scaling, peeling, or itchy skin
  • Worsening acne
  • Retinoid dermatitis, or small patches of irritated, darkened skin
  • Increased temperature sensitivity

While some of these side effects – e.g., worsening acne – are counterintuitive and even disheartening, they are expected and should go away after a few weeks of treatment.

If they do not, speak with your dermatologist. You should also seek medical care if you have any more severe side effects that seem connected to your prescription retinoid. For example, painful blistering and burning skin are rare side effects of retinoid use, but they can happen.

Best Prescription Retinoids

Save Big on High-Quality Retinoids Through an Online Canadian Pharmacy and International Drugstore

When American patients are interested in benefiting from prescription retinoids, they often have no choice but to pay sky-high medication costs at their local drugstore. Alternatively, they may be able to find online pharmacies that sell strong skincare treatments, but it can be challenging to assess product safety online.

Either way, patients are out a lot of cash and time. If they’ve bought poor-quality or scammy products, they could even be experiencing unwanted side effects or battling rashes.

Investing in your skin’s health shouldn’t be complicated or expensive (and it definitely shouldn’t be dangerous).

We agree. That’s why we provide high-quality brand-name prescription retinoids and a top-tier customer experience.

We’re also certified by the Canadian International Pharmacy Association, a reputable organization overseeing international and Canadian drugs websites' safety, quality, and security. As a result, shopping through should always be an intuitive, time-saving, and cost-saving experience.

If you have any questions about how we can help you or want to chat directly with a pharmacist about your prescription, reach out to our seven-day-a-week customer service desk. One of our friendly representatives will be more than happy to speak with you or even help you place an order over the phone.

Call us at 1-866-539-5330, or contact us online. We look forward to supporting you and your health goals!

The information provided on the website is intended to facilitate awareness about healthcare products and medical conditions generally but it is not a substitute for professional medical attention or advice. You should always speak with a qualified healthcare practitioner before taking any prescription or non-prescription drug.
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